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Glycopyrronium bromide (the active substance in Glycopyrronium bromide tablets) belongs to a group of medicines called quaternary ammonium anticholinergics, which are agents that block or reduce the transmission between nerve cells. This reduced transmission can de-activate the cells that produce saliva.

Glycopyrronium bromide tablets are indicated for the symptomatic treatment of severe sialorrhoea (chronic pathological drooling) due to chronic neurological disorders of childhood onset in patients 3 years and older.

Glycopyrronium bromide tablets are used to treat excessive production of saliva (sialorrhoea) in patients suffering from long term neuroligical disorders which have occurred in child hood, in patients aged 3 years and older.

Sialorrhoea (drooling or excessive salivation) is a common symptom of many diseases of the nerves and muscles. It is mostly caused by poor control of muscles in the face. Acute sialorrhoea may be associated with inflammation, dental infections or infections of the mouth. Glycopyrronium bromide tablets act on the salivary glands to reduce production of saliva.



DO NOT take Glycopyrronium bromide tablets if you:

  • are allergic to glycopyrronium bromide or any of the other ingredients of this medicine (listed in section 6 of the Patient Information Leaflet)

  • are pregnant or breast feeding

  • suffer from glaucoma (increased pressure in the eye)

  • are unable to completely empty the bladder (urinary


  • have severe kidney disease

  • have an enlarged prostate gland (prostatic hypertrophy)

  • have an obstruction of the stomach (pyloric stenosis) or

    bowel causing vomiting

  • have ulcerative colitis (inflammation of the intestine)

  • have diarrhoea (frequent, loose watery stools)

  • have stomach ache and swelling (paralytic ileus)

  • have myasthenia gravis (muscle weakness and fatigue)

  • are over 65 years of age

  • are taking any of the following medicines (see section Other

    medicines and Glycopyrronium bromide tablets of the Patient Information Leaflet):

    • potassium chloride solid oral dose;

    • anticholinergic medicines.


Tell your doctor if you are not sure about any of the above.

Warnings and precautions
Talk to your doctor or pharmacist before taking Glycopyrronium bromide tablets if you (or the patient) have:

  • heart disease, irregular heartbeats or high blood

    pressure, because this medicine can cause a change to

    your normal heart rate

  • digestive disorders (constipation, chronic heartburn and


  • a high temperature (fever), as this medicine will reduce the

    amount you may sweat, making it harder for your body to

    cool down

  • inability to sweat normally

  • kidney problems or difficulty passing urine, because this

    medicines dose may need to be reduced.

  • abnormal blood brain barrier (the layer of cells surrounding

    the brain)

If you are not sure if any of the above applies to you, talk to a doctor or pharmacist before taking this medicine.


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